Tzu-Sheng Hsu Selected Research

7- chloro- 6- piperidin- 1- ylquinoline- 5,8- dione

4/2011	7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration.
10/2008	7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.

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Tzu-Sheng Hsu Research Topics

Disease

5	Neoplasms (Cancer) 01/2018 - 05/2004
4	Colorectal Neoplasms (Colorectal Cancer) 12/2009 - 12/2006
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019 - 01/2019
2	Carcinoma (Carcinomatosis) 04/2011 - 05/2004
1	Hypoxia (Hypoxemia) 10/2020
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Infections 01/2018
1	Inflammation (Inflammations) 01/2018
1	Stomach Neoplasms (Stomach Cancer) 01/2018
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2016
1	Hypersensitivity (Allergy) 02/2015
1	Lymphoma (Lymphomas) 08/2014
1	Necrosis 03/2009
1	Lung Neoplasms (Lung Cancer) 10/2008
1	Genomic Instability 12/2007

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 10/2008 - 05/2004
3	dinophysistoxin 1IBA 01/2019 - 08/2014
3	Pharmaceutical PreparationsIBA 12/2009 - 12/2006
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2009 - 12/2006
3	SecurinIBA 06/2008 - 12/2006
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2019
2	UbiquitinIBA 01/2018 - 08/2014
2	7- chloro- 6- piperidin- 1- ylquinoline- 5,8- dioneIBA 04/2011 - 10/2008
2	DNA (Deoxyribonucleic Acid)IBA 12/2009 - 06/2008
1	Transcription Factors (Transcription Factor)IBA 10/2020
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2018
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2018
1	Death Domain ReceptorsIBA 01/2018
1	CASP8 and FADD-Like Apoptosis Regulating Protein (FLIP-S)IBA 01/2018
1	Interleukin-17 (Interleukin 17)IBA 01/2016
1	Ligases (Synthetase)IBA 08/2014
1	Protein Kinases (Protein Kinase)IBA 08/2014
1	Matrix Metalloproteinases (MMPs)IBA 03/2009
1	NF-kappa B (NF-kB)IBA 03/2009
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 10/2008
1	CaspasesIBA 10/2008
1	p38 Mitogen-Activated Protein KinasesIBA 06/2008
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2004
1	SurvivinIBA 05/2004

Therapy/Procedure

1	Therapeutics 01/2018
1	Transplantation 02/2015